Not known Factual Statements About megatomi.com
Not known Factual Statements About megatomi.com
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Rapidly obtain sections as skinny or thick as your application involves, without worrying about shedding or distorting precious tissue samples.
Megatome is often a vibrating microtome made to area a broad choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With high blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform surface area profile, and also small tissue destruction and knowledge decline.
Antibodies may take weeks to diffuse through only a few millimeters of tissue, with a steep labeling gradient from surface to Main.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and includes a distinctive deflection Manage mechanism.
SE utilizes a rotational electric industry to disperse really electromobile molecules (for instance antibodies or surfactant micelles) through a porous sample without harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,
Our preformulated EasyIndex Answer raises and homogenize the refractive index of delipidated tissue samples, rendering them fully clear. This permits mild penetration into the sample and makes certain the acquisition of substantial-resolution, in-target image information.
Megatome can be a novel microtome that permits for top-precision sectioning of a wide range of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with minimal tissue hurt and information decline.
eFLASH is actually a rapid tissue labeling procedure that allows for uniform full-organ staining in 20 rounds of labeling.
The SmartSPIM gentle sheet microscope offers unparalleled resolution and acquisition velocity all through intact tissue volumes, when its modular style helps you to update and customise personal factors.
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Leverage the Distinct+ tissue clearing strategy, coupled with eFLASH and patented stochastic electrotransport technologies, to rapidly distinct and label whole organs. Crucial highlights and characteristics involve:
Our novel SHIELD tissue preservation approach kinds intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.